Effect of the combination of Silybrum marianum and Lycopodium clavatum on some biological markers for monitoring chronic hepatitis B virus patients

Viral hepatitis B is a disease for which no curative treatment available to date. The objective of this study evaluate the effect Silybrum marianum and Lycopodium clavatum preparations on biological parameters viral follow-up.
 Material methods: This was longitudinal period 5 months. population consisted consenting chronic patients. A questionnaire used collect sociodemographic information medical history One Step Rapid Test HBV-2210305 Biolabo kits were test serological transaminases. load determined using real-time PCR technique. decoctions made from leaves rhizomes Sylibum associated with floral juice clavatum. evaluation decoction done by comparing values between beginning after 3 months treatments.
 Results: Seven out nine patients chronically infected virus in active phase. After 90 days treatment, we noted persistence AgHbs all but disappearance AgHbe 75% Mean transaminase activity decreased significantly (P=0.045).
 Conclusion: preparation leads normalization Alanine Amino transferase activities (AAT), loss HBe antigen decrease three treatment.
 Keywords: Chronic B, marianum, clavatum, decoctions, load.